Publications

Immunomodulatory activities of alpha lipoic acid with a special focus on its efficacy in preventing miscarriage

Introduction: Alpha lipoic acid (ALA) is an essential mitochondrial co-factor and, as a free
molecule, it can exert multi-level immunomodulatory functions. Both ALA and its reduced form,
dihydrolipoic acid (DHLA), are believed to be able to chelate heavy metals, to regenerate essential
antioxidants and to repair important molecules damaged by oxidation. The largest part of the effects
of ALA/DHLA …

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Publications

Il 17α-idrossi progesterone-caproato nella pratica clinica ostetrica

INSUFFICIENZA DELLA FASE LUTEALE
L’ insufficienza del corpo luteo e la conseguente incapacita riproduttiva e stata ipotizzata da Jones (Jones, 1976). In seguito sono state riportate stime notevolmente differenti della presen­za di questa sindrome nell’aborto ricorrente. Le prime stime variavano dal 20 al 60% (Doody and Carr, 1991) ma altri Autori hanno riportato percentuali …

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Does myo-inositol effect on PCOS follicles involve cytoskeleton regulation?

Inositol metabolism is severely impaired in follicles obtained from cystic ovaries, leading to deregulated insulin transduction and steroid synthesis. On the contrary, inositol administration to women suffering from polycystic ovary syndrome (PCOS) has been proven to efficiently counteract most of the clinical hallmarks displayed by PCOS patients, including insulin resistance, hyperandrogenism and oligo-amenorrhea. We have recently …

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