Infertility / Myo-Inositol

Inositol safety clinical evidences

Myo-inositol is a six carbon cyclitol that contains five equatorial and one axial hydroxyl groups. Myo-inositol has been classified as an insulin sensitizing agent and it is commonly used in the treatment of the Polycystic Ovary Syndrome (PCOS). However, despite its wide clinical use, there is still scarce information on the myo-inositol safety …

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Infertility / Myo-Inositol

The D-chiro-inositol paradox in the ovary

The D-chiro-inositol–to–myo-inositol ratio is regulated by an insulin-dependent epimerase. Enzyme activity varies among tissues, likely owing to the specific needs of the two different molecules. We hypothesize that in the ovaries of polycystic ovary syndrome patients, epimerase activity is enhanced, leading to a local myo-inositol deficiency which in turn is responsible for the poor oocyte …

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Myo-Inositol / Publications

Myo-inositol rather than D-chiro-inositol is able to improve oocyte quality

Objective: Polycystic ovary syndrome (PCOS) is the most common cause of infertility due to menstrual dysfunction, and the most promising treatments for this disease are insulin sensitising agents. Myo-inositol and D-chiro-inositol are insulin sensitizing agents used in PCOS treatment. In the present paper, we aimed to compare the effects myo-inositol and D-chiro-inositol on …

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Myo-Inositol / Publications

The effect of a combination therapy with myo-inositol and a combined oral contraceptive pill versus a combined oral contraceptive pill alone on metabolic, endocrine, and clinical parameters in polycystic ovary syndrome

Aim. Compare the effects of a combined contraceptive pill (OCP) in combination with myo-inositol (MI) on endocrine, metabolic, and clinical parameters in patients with polycystic ovary syndrome (PCOS).

Methods. One hundred fifty-five patients with PCOS were enrolled in this prospective, open-label clinical study. Patients were assigned to receive oral treatment with OCP alone (estradiol (EE) 30 …

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Publications

Inositol activity in oligoasthenoteratospermia – An in vitro study

Background: Oligoasthenoteratospermia, a reduction in motilty and number of spermatozoa and a change in their morphology, is one of the most relevant causes of infertility in men. One of the factors, which may influence male infertility is linked to the production of reactive oxygen species (ROS) by morphologically altered spermatozoa. Spermatozoa …

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Publications

Inositol activity in oligoasthenoteratospermia An in vitro study

Background: Oligoasthenoteratospermia, a reduction in motilty and number of spermatozoa and a change in their morphology, is one of the most relevant causes of infertility in men. One of the factors, which may influence male infertility is linked to the production of reactive oxygen species (ROS) by morphologically altered spermatozoa. Spermatozoa are more …

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Publications

Il Myo-Inositolo nella pratica clinica ostetrica-ginecologica

E’ sempre motivo di soddisfazione leggere in anteprima una monografia scienti­fica per poi presentarla all”attenzione della comunità scientifica. E’ una soddisfa­zione ancora maggiore se a redigerla sono quattro illustri esperti sull’argomento: Enrico Papaleo e Vittorio Unfer, con i quali ho stretti rapporti di amicizia e stima, e Jean-Patrice Baillargeon e Chiu Tak Yu, …

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Melatonina e sistema riproduttivo maschile

La più semplice spiegazione del perché la melatoni­na abbia un effetto sul sistema riproduttivo, viene, an­cora una volta, dall’ attenta osservazione della natura. In­fatti, in natura, un numero considerevole di specie ani­mali, escluso l’uomo, è sottoposto ad un ritmo ripro­duttivo che consente la nascita dei piccoli durante il pe­riodo più favorevole. II fenomeno è particolarmente im­portante …

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The sutures in dentistry

In oral surgery, the last phase of a surgical operation is represented by the tissues suture, that allows the wound lips edges approximation and their stabilization, to promote haemostasis, to avoid the alimentary residues accumulation on the incision line and allow the first intention healing. A good suture avoids that the displacing forces …

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